Recombinant factor VIIa for life-threatening post-partum haemorrhage
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چکیده
منابع مشابه
Recombinant factor VIIa for life-threatening post-partum haemorrhage.
The treatment of life-threatening post-partum haemorrhage (PPH) still remains challenging, and hysterectomy may be required to control the bleeding. We present 12 cases of severe PPH treated with recombinant factor VIIa (rFVIIa). We briefly describe the causes of the haemorrhage and the medical and surgical interventions before rVIIa administration. In 11 women there was a partial or good respo...
متن کاملUse of recombinant factor VIIa to treat life-threatening non-surgical bleeding in a post-partum patient.
Ongoing bleeding from patients who have an acquired coagulopathy post-surgery is a common problem. Strategies that are available to combat this problem revolve around the replacement of coagulation factors, platelets, and red blood cells as necessary. These strategies are not always successful and a more direct approach to activating the coagulation system can be more effective and in some inst...
متن کاملRecombinant factor VIIa in massive obstetric haemorrhage.
the severity of hypertensive attacks. The other recommended agent phentolamine, a short-acting alpha blocker, could not be used due to unavailability in our institution during this case. Magnesium sulphate is routinely used to control arrhythmias and hypertension in patients undergoing cardiovascular surgery and in the Caesarean section of preeclamptic patients or ICU patients. However, magnesi...
متن کاملUse of recombinant factor VIIa for major haemorrhage.
EDITOR: Haemorrhage associated with trauma and surgery remains a significant cause of death. The development of coagulopathic bleeding is often difficult to manage. Recombinant-activated factor VII (rFVIIa, NovoSeven®; Novo Nordisk, Bagsvaerd, Denmark), which is structurally similar to the naturally occurring activated coagulation factor VII, is licensed for use in patients with haemophilia A o...
متن کاملPost-Partum Haemorrhage.
Post-partum haemorrhage is defined as being "excessive bleeding from any part of the genital tract after the birth of a child." Some authorities make a hair-splitting definition and describe intra-partum haemorrhage when excessive bleeding occurs before the placenta has been delivered, and confine the term post-partum haemorrhage to excessive bleeding after the completion of the third stage of ...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2005
ISSN: 0007-0912
DOI: 10.1093/bja/aei594